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Essay / Research Paper Abstract
10 pages in length. The quest for life extension continues to preoccupy mankind's scientific endeavors. Research in the area of increased longevity in lower organisms has produced findings associated with environmental (external) implications (Jazwinski, 1996), the discovery of longevity genes (Varmus, 1997), caloric limitations to produce beneficial metabolic changes (Yamaza et al, 2002) and achieving the same benefits of calorie limitations without the associated depravation by way of molecular mimicry (Anonymous, 2002). Bibliography lists 11 sources.
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10 pages (~225 words per page)
File: LM1_TLCLfSpn.rtf
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(external) implications (Jazwinski, 1996), the discovery of longevity genes (Varmus, 1997), caloric limitations to produce beneficial metabolic changes (Yamaza et al, 2002) and achieving the same benefits of calorie limitations
without the associated depravation by way of molecular mimicry (Anonymous, 2002). "Caloric restriction has been shown to extend lifespan in almost every organism it has been tried on, from
rats to fish to spiders, all the way down to worms and yeast...If we can understand the molecular basis of whats going on in the lower organisms, we might have
a chance to understand how it works in humans, too. What we really want to do is to be able to mimic calorie restriction without having to starve ourselves"
(Anonymous, 2002). II. FLIES Assume that investigators crossed a strain of flies carrying the dominant eye mutation lobe on the second chromosome
to a strain homozygous to the second chromosome recessive mutations smooth abdomen and straw body. The F1 lobe (Lb) females were backcrossed to homozygous smooth abdomen (sa), straw bodied
(sb) males and the following F2 phenotypes were observed : sa,sb: 820; Lb: 42; sb: 58; sa: 148; Lb,sb: 152. (A) Give the gene sequence and map units between
these three loci. (B) What is the coefficient of coincidence. When determining these calculations, it is important for the student to
consider the relationship between and among the various components as they relate to extended life span. The issue of mutation is one the student will want to focus upon
in particular, inasmuch as contemporary science has discovered that mutation is not necessarily a negative aspect of reproduction in this sense. In todays world, mutation has become a critical
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