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Essay / Research Paper Abstract
An 11 page research paper on pulmonary tuberculosis in which the writer focuses upon the disease's causes, frequency, spread, and effects. Cavities, or holes in the lungs can develop in patients with pulmonary tuberculosis when the host response to the infecting organisms unleashes its destructive potential on the host cells as well, leading to liquefaction of tissue. Specific forms of pulmonary tuberculosis such as miliary TB are discussed as well. Recommended medical treatments are detailed. Bibliography lists 9 sources.
Page Count:
11 pages (~225 words per page)
File: D0_Tubercul.doc
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both of them soon after died from the disease. Later, in the year 1874, an American physician named Edward Livingston Trudeau, who was also afflicted with tuberculosis, founded the Trudeau
Laboratory in Saranac Lake, New York. It became a model sanatorium, the kind that for a long time would be main location for tuberculosis treatment worldwide. Not that much later,
a German scientist named Robert Koch discovered the causative organism, the tubercle bacillus, in 1882; in 1890 he developed the tuberculin test for diagnosis of the disease. Almost four decades
later, a vaccine, called the BCG (Bacillus Calmette-Gu?rin) vaccine, for individuals exposed to tuberculosis was developed by the French bacteriologists Albert L?on Calmette and Alphonse F. M. Gu?rin.
The first specific chemotherapeutic agent for tuberculosis became available when, in the mid 1940s, Selman Abraham Waksman (an American microbiologist) discovered streptomycin. This discovery was followed by the
development in 1948 of PAS (para-aminosalicylic acid), and later by isoniazid and other drugs that revolutionized the treatment of tuberculosis. The number of deaths from the disease in the United
States declined nearly 50% from about .02 percent population in 1904 to about .01 percent in 1980. Beginning in 1985, however, the number of cases in the United States began
to increase because of the AIDS virus (Tuberculosis, 1990- Free Press). II. Analytical Discussion: Pulmonary Tuberculosis; Todays New Imp Cavities,
or holes, in the lungs can develop in patients with pulmonary tuberculosis when the host response to the infecting organisms unleashes its destructive potential on the host cells as well,
leading to liquefaction of tissue. The World Health Organization estimated that there were about 8 million new cases of tuberculosis and 2.9 million deaths from tuberculosis worldwide in 1990.
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