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Essay / Research Paper Abstract
A 4 page paper describing the method by which ribosomes synthesize proteins in the cell’s cytoplasm. The paper identifies amylase as being one of the body’s proteins, one so specific that its presence in blood confirms diagnosis of pancreatitis, a potentially fatal disease. Includes one figure. Bibliography lists 4 sources.
Page Count:
4 pages (~225 words per page)
File: CC6_KSproteinSyn.rtf
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Unformatted sample text from the term paper:
been complete for several years now, and the general process of protein synthesis is well understood. We are far from knowing all there is to know about it, however,
as it has become apparent that protein synthesis can be affected by several substances and conditions previously unknown. Discovery History It was all
unknown in the post-war years, however. A major breakthrough in learning the secrets of protein synthesis came in 1956 when George Palade realized the ribosome as the site of
protein synthesis (History of Biology and Medicine, 2001). Three years later, Brener, Jacob and Meselson discovered mRNA to complete the puzzle that other researchers had identified.
The existence and function of mRNA was sufficient to allow researchers to accurately describe the process of protein biosynthesis. In 1960, "Francis Jacob and
Jacques Lucien Monod proposed the operon hypothesis for the regulation of enzyme synthesis" (Park, 2003) to provide a more complete perspective of the total process. In 1964, Nirenberg and
Leder published "RNA Codewords and Protein Synthesis: The Effect of Trinucleotides upon the Binding of sRNA to Ribosomes." The Process Protein synthesis is
the product of two sub-processes, transcription and translation. All protein synthesis begins within the cells nucleus, inside the DNA molecule. The DNA double helix begins to "untwist" under
the influence of RNA polymerase. Source: (Protein Synthesis, n.d.) Transcription In the transcription
phase of protein synthesis, one "strand of the DNA double helix is used as a template by the RNA polymerase to synthesize a messenger RNA (mRNA)" (Protein Synthesis, n.d.).
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