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A 9 page research paper that, first of all, describes prostanoid receptors and their role in human physiology and then briefly summarizes current scientific research on this topic. Bibliography lists 6 sources.
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9 pages (~225 words per page)
File: D0_khprorec.rtf
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being precursors of prostaglandin production (Narumiya, Sugimotor and Ushikubi, 1999, p. 1193). Prostanoids also modulate neuronal activity, by either inhibiting or stimulating neurotransmitter release. They sensitize sensory fibers to noxious
stimuli, and can also induce basic neural activity, such as fever generation or sleep induction (Narumiya, Sugimotor and Ushikubi, 1999). Additionally, prostanoids regulate activities in regards to blood platelets, both
positively and negatively, and are involved in vascular homeostasis and hemostasis (Narumiya, Sugimotor and Ushikubi, 1999). The following examination of literature regarding the latest research on prostanoid receptors suggests that
this line of investigation may eventually result in a number of pharmacological products that promote health by addressing the effects of prostanoid receptors, which have been shown to affect a
wide variety of bodily system. Due to the fact that prostanoids are produced by fatty acids, they are typically regarded as hydrophobic compounds (Narumiya, Sugimotor and Ushikubi, 1999). Also,
due to this observation, it was believed earlier that they were incorporated into the cell membrane and exerted their action via perturbing lipid fluidity (Narumiya, Sugimotor and Ushikubi, 1999). This,
however, has not proven to be the case. The concept of prostanoid action operating via prostanoid receptors evolved from several different lines of research. First of all, prostanoids were shown
to be not as hydrophobic as they were once thought and that they do not incorporate into or permeate cell membranes (Narumiya, Sugimotor and Ushikubi, 1999). Also, research shows that
each prostanoid has its own unique activity profile, which is often similar to but does not precisely overlap other prostanoids (Narumiya, Sugimotor and Ushikubi, 1999). This became evident from comparing
the potencies of various prostanoids and their synthetic counterparts on various tissues using bioassay (Narumiya, Sugimotor and Ushikubi, 1999). Studies pursing this line of investigation suggested the presence of
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