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Essay / Research Paper Abstract
3 pages in length. The writer discusses the pathophysiology of Phenytoin, the drug most commonly prescribed for epilepsy. Bibliography lists 6 sources.
Page Count:
3 pages (~225 words per page)
File: LM1_TLCphenytoin.rtf
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Unformatted sample text from the term paper:
not an available option unless the condition stems from head or brain injuries, contact with poisons such as lead, nutritional deficiencies, photosensitivity or knowledge of it being hereditary. In
the case of genetics, there is no guarantee the individual will ever develop the disorder. In non-technical terms, epilepsy is a short circuit in the brain. Once the
tests have been run to determine a possible triggering basis, it may be found that the individual has one of several pathophysiological conditions linked to the attacks, such as migraine-related
seizures; photosensitive epilepsy most commonly associated with, for example, the flickering nature of video games; or occipital epilepsy associated with the brains occipital lobe (Viniker, 2008). In technical terms,
it is a series of misfires of the neurosynaptic function that ultimately sends confused signals to the body, thus creating the uncontrolled fits. Although epilepsy research is making progress,
advances in understanding drug resistance have been hampered by the complexity of the underlying neuronal systems responsible for epileptic activity (Wendling, 2008, pp. 889-896).
The anticonvulsant prescribed more often than any other for humans is Phenytoin, a highly effective drug for generalized seizures due to its efficacy and easy dispensability by pill,
liquid or injection. In addition, its side effect rating is better than the other available therapy drugs; however, that does not mean there are no side effects at all,
inasmuch as a higher dose is often required, which equates to a higher chance of experience such side effects as drowsiness, dizziness, ataxia, nausea, sleep disturbances and headache (Bazire, 2005).
Since anticonvulsive drugs are metabolized in the liver, problems such as cirrhosis (degenerative disease of connective tissue) and necrosis (death of tissue), the former of which is considered one
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