Sample Essay on:
PARKINSON'S DISEASE AND GROWTH FACTORS

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Essay / Research Paper Abstract

This 5-page paper focuses on the use of growth factors as potential treatments for those with Parkinson's disease. Bibliography lists 3 sources.

Page Count:

5 pages (~225 words per page)

File: D0_MTpardis.rtf

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Unformatted sample text from the term paper:

However, certain types of gene therapies are currently underway that could promise hope and relief for Parkinsons sufferers. These are called growth factors -- and they work by allowing neurons to regenerate their axon (Pressman, 2004). These therapies, although not extensively tested, provide hope for a disease that has typically had no cure (as mentioned before). However, they are still mostly in the testing phase (with some human experimentation), meaning a good deal of work still needs to be undergone until such time when these therapies are available for general use. For example, Nerve Growth Factor (or NGF) is the best-known of the "growth factor" therapies (Pressman, 2004), as well see later on in this paper, there are other growth factor therapies in use as well. Growth therapies work, as there tends to be a correlation between a tissues ability to produce NGF and the amount of sympathetic and sensitive nerves it has (Pressman, 2004). In other words, the growth factor and tissue work together to simulate nerve activity. Basically, something like NGF is synthesized by fibroblasts and Schwann cells as well -- and these bind to receptors that are on the surface of nerves (Pressman, 2004). What happens then is that they are transported to the cell body that is missing the appropriate growth factor on its own (Pressman, 2004). This can help with (at least in theory) nerve regeneration. In the past several years, several of these "growth factors" have been uncovered and small trials held with them. Parkinsons, in its most basic sense, is when brain cells stop producing dopamine, which helps control muscle motion. ...

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