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Essay / Research Paper Abstract
This 5 page paper evaluates an article submitted by a student entitled "Casponfungin versus Liposomal Amphotericin B for Empirical Antifungal Therapy in Patients with Persistent Fever and Neutropenia." The research experiment is summarized and critiqued. No additional sources cited.
Page Count:
5 pages (~225 words per page)
File: RT13_SA445art.rtf
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Unformatted sample text from the term paper:
Journal of Medicine, 351 (14), 1391- 1401. In this journal article, authors examine the plight of subjects who experienced persistent fever as well as neutropenia and who received empirical
therapy (Walsh, Teppler & Donowtiz, 2004). Then, what is examined next is the use of conventional versus liposomal amphotericin B (2004). Caspofungin is viewed as an alternative method to
amphotericin B (2004). In a double-blind trial, authors looked at safety and efficacy of caspofungin and it was noted in comparison with liposomal amphoterician B (2004). The study was conducted
from 116 sites and in 26 countries (2004, p.1392)). Patients in the study are grouped into high and low risk categories (2004). In evaluating this article relaying this important study,
it does appear that authors do clearly define the specifics of the study and pay particular attention to the study population. In fact, the article does point out the specific
criterion necessary for persons to participate in the study. For example, participants were required to be at least 16 years of age and they had to have received treatment for
cancer (Walsh, Teppler & Donowtiz, 2004). Other criteria are laid out as well and authors do a good job in conveying the specifics of the experiment. When patients are
first enrolled, their entry is broken down by risk in addition to whether or not they had ever received antifungal prophylaxis (2004). However, by distributing patients into risk groups, there
is the problem of categorization. Again, this is a judgment call in terms of creating two such groups. However, attention to whether or not patients had received antifungal prophylaxis in
the past does lend authors a bit of insight into reasons for success if in fact these patients do well. In evaluating results however, the criteria are not as clear.
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