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Essay / Research Paper Abstract
Hypoglycemia (or Hypoglycaemia with the UK spelling) is a serious, but often avoidable condition. This 7 page paper reviews 5 research papers that examine different aspects of the condition and its' treatment or management. The first article looks at " Brain Glucose Uptake and Unawareness of Hypoglycaemia in Patients with Insulin-Dependent Diabetes Mellitus", the second examines the causes of causes of hyperglycaemia and hypoglycaemia in adult inpatients. The third article reviews research that argues there will be a reduction in severe hypoglycaemia with the use of long-term continuous subcutaneous insulin infusion (CSII) in type I diabetes. The last two article consider the treatment and control in older patients, firstly looking at risk factors and then the potential risk of hypertensives. The bibliography cites 5 sources.
Page Count:
7 pages (~225 words per page)
File: TS14_TEhypogly.rtf
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Unformatted sample text from the term paper:
Boyle et al, (1995) publish a research article entitled Brain Glucose Uptake and Unawareness of Hypoglycaemia in Patients with Insulin-Dependent Diabetes Mellitus. This research examined patients who had insulin-dependent diabetes
mellitus (IDDM) where the manifestation of the condition and its treatment resulted in the mean plasma glucose concentration being at near normal levels (Boyle et al, 1995). In these patients
it had been noted there was an increase risk of coma or seizure as a result of an unawareness of the potential development of hypoglycaemia. The hypothesis of this study
was that at the beginning of hypoglycaemia in these patients there would not be abnormal glucose intake and as such there would not be a sympathoadrenal activation which would mean
an unawareness of hypoglycaemia (Boyle et al, 1995). This was studied with a sample of 24 patients that have IDDM which were divided into three groups according to their
glycosylated haemoglobin level values (Boyle et al, 1995). These values were then compared with the brain glucose level take up in a sample of 15 normal patients. There
was also a comparison between the hypoglycaemic-symptom scores of both subject groups and the counter regulatory hormones plasma concentrations (Boyle et al, 1995). The results were interesting. In the
IDDM group with the lowest glycosylated hemoglobin value group, those with a value of +0.6 +/- 2.0 mg there was no change in the uptake of glucose measured in the
brain (Boyle et al, 1995). However, for the intermediate group and the higher group there were falls of 1.3 +/- 1.0 mg per 100g per minute and 1.8 +/-
1.6 mg per 100g per minute respectively (Boyle et al, 1995). In the normal group there was also a fall of 1.6 +/- 1.8 mg per 100g per minute (Boyle
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