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Essay / Research Paper Abstract
A 5 page paper reviewing and comparing two articles, one from the British The Lancet, the other from American Family Physician, both refereed medical journals. Both of these articles are useful in providing additional knowledge of GBS in general terms, one in the fact that some types of polio vaccines (or the order in which those types of vaccines are used) may have some connection with increased incidence of GBS; the other in possible treatment regimes for established cases. Both, however, are clear in their message that much more remains unknown about GBS and that there is a need for additional research in the causes of and treatments for the condition. Bibliography lists 2 sources.
Page Count:
5 pages (~225 words per page)
File: CC6_KSG-Barre.doc
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Unformatted sample text from the term paper:
weakness in his extremities, a mild respiratory infection, nausea and general malaise. These symptoms were followed by a flaccid paralysis that was accompanied by alternating sensations of tingling and
numbness, particularly in his hands and feet. All of his symptoms matched those of Guillain-Barre syndrome, and his physicians began treatment immediately to avoid the threat of respiratory failure
that often follows the general flaccid paralysis as it intensifies. In this case, the problem was found to be the arsenic that the mans wife had been using to
season his food. Doctors were able to counteract the effects of the arsenic; the couple was left to deal with their marital problems themselves.
Guillain-Barre syndrome is relatively rare, but it is disturbing in that its cause remains unknown. Complete recovery is common when medical attention is sought early enough in
the development of the disease, but mechanical respiratory intervention often is necessary in the acute phase to avoid respiratory failure resulting in death.
The Lancet Researchers have agreed that Guillain-Barre syndrome (GBS) appears to be the "result of an immune process and that certain infections
may act as triggers. A front-running candidate for the latter is Campylobacter jejuni infection. Since vaccines exert their effect through immune processes, and live vaccines also infect the recipient, it
is tempting to implicate vaccines in the aetiology of GBS" (Salisbury, 1998; p. 79). The chance of development of the condition is one reason that diphtheria-tetanus-pertussis (DTP) vaccine often
is discouraged in pediatrics as preventive vaccination. The chance of developing GBS also has been used in arguments against routine vaccination against measles, mumps and rubella (MMR).
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