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Essay / Research Paper Abstract
This 6 page paper considers how epidermal stems cells may play a role in healing wounds. The paper discusses the healing process and looks at recent research which indicates the importance of dermal sheath cells in speeding and increasing the quality of wound healing. The bibliography cites 19 sources.
Page Count:
6 pages (~225 words per page)
File: TS14_TEstemce.rtf
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Unformatted sample text from the term paper:
some cells and restraining growth of other cells to produce the effective healing process. By understanding the role of stem cells in the healing of the epidermal layer more effective
treatments may be developed that utilised the healing mechanisms already in place. The formation of the skin is such that there are two layers; the keratinized stratified Epidermis and
the connective tissues which is a collagen rich dermal layer (Martin, 1997). These are also two different and separately defined pathways of the development of the cells under normal
conditions (Watts, 1998). However, when there is a wound to be healed that pattern can change, with the need to seal the skin layer. For example the hair follicle which
projects deeper into the body may demonstrate the way that stem cells react. If a wound occurs then hair follicle keratinocytes can transfer to the interfollicular epidermis where they can
then repopulate the area (Watts, 1998). The opposite is also true, if an empty hair shaft has interfollicular keratinocytes transferred to it, these will then, upon contacting the dermal papilla
cells to form the shaft of a hair (Watts, 1998). When other animals such as rabbits are examined, it has been fond that there is a higher speed of full
thickness dermal renewal, this has been attributed to the increased level of hair follicle densities and the migration and development of the differentiated cells (Jahoda and Reynolds, 2001). This
demonstrated the level of potential held by these cells, indeed, in looking at the characteristics of stem cells and epidermal renewal this process may be better understood. There are several
properties that may be attributed to stem cells, they are undifferentiated, whilst the body is living they can divide with no limits, when division takes place each daughter cell has
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