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Essay / Research Paper Abstract
This 3 page paper summarizes an article by Colon and Raff (2003) entitled “Differences in the way a mammalian cell and yeast cells coordinate cell growth and cell-cycle progression” which looks at the role of cell check points and the importance of extracellular signalling for mammalian cells when researched with the use of Schwamm cells. The bibliography cites 1 source.
Page Count:
3 pages (~225 words per page)
File: TS14_TEcellgrow.rtf
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Unformatted sample text from the term paper:
biologists. Cells in culture will usually double their mass prior to division, but the way the division is coordinated to ensure that cell size is maintained. In the article by
Colon and Raff (2003) this process takes place, comparing rat Schwann cells with yeast cells. Cell growth takes place at all stages of the cell cycle with the exception
of the M phase. Research indicates yeast cells are coordinated with the use of check points at G1 and/or G2 where the cell size is checked, the cycle can be
paused at this point if the cells have not reached the required size to allow further growth to take place, only when the cells are the correct size will the
grow stage move onto the S or M phase. The actual check point mechanism is not fully understood, but it is thought that there is a link between the threshold
levels and some cell cycle activators plays an important role in this process. The process for mammalian cell vision is not known, but was generally thought to have similar checkpoints
in the process. In yeast cells it is also known that small cells we grow at a smaller rate than large cells, which means that there must be check
points as there is a constant average size in a yeast cell population, if this were not the case cells that were born larger would also keep growing faster and
over time there would be an increase in the population average cell size. Nutrients regulate the yeast cell size check points, as more nutrients will increase the rate of
growth and division, in a rich nutrient medium the rate is faster than in a poor nutrient medium, but the rate resumes when placed back into the rich medium.
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