Here is the synopsis of our sample research paper on Colon (Colorectal) Cancer. Have the paper e-mailed to you 24/7/365.
Essay / Research Paper Abstract
4 pages in length. The writer briefly discusses genetic mutations, symptoms, causes and treatment as they relate to colorectal cancer. Bibliography lists 6 sources.
Page Count:
4 pages (~225 words per page)
File: LM1_TLCcolcncr.rtf
Buy This Term Paper »
Unformatted sample text from the term paper:
is recommended upon detection. Once mutation occurs, the cells can attach themselves anywhere along the colon, an area of large intestine four to five feet long; the last six
inches after that is the rectum and is often associated with the mutant cells to create colorectal cancer. Most likely polyps include adenomas, hyperplastic and inflammatory, the latter of
which may develop after ulcerative colitis and can become cancerous. The biological risk of getting colon cancer stems from a history of family genetics that can include two rare
conditions: FAP (familial adenomatous polyposis) whereby the colon and rectum become inundated with thousands of polyps and the more common HNPCC (hereditary non-polyposis colon cancer) or Lynch syndrome whereby colon
cancer develops at an age much earlier than then standard 50 (Colon Cancer and Polyposis FAP - HNPPC?). II. MUTATED GENES FAP
is genetically passed on in the form of an autosomal dominant trait, which will continue to be transmitted by carriers to the point where offspring will develop polyposis coli fifty-percent
of the time, a condition caused by the adenomatous polyposis coli [APC] gene that exists upon chromosome 5. HNPCC is associated with Lynch syndrome I (colonic tumors) and
II (colonic and additional tumors such as endometrial, ovarian or breast. According to the Colon Cancer Review, "the molecular genetic marker reflective of HNPCC is microsatellite instability" (Colon Cancer
and Polyposis FAP - HNPPC?), which occurs as a direct result of mutations in DNA mismatch repair genes hMSH2, hMLH1, hPMS1 and hPMS2. III. SYMPTOMS Symptoms are not always
the best way to determine the presence of colon cancer due to the fact that early onset often goes undetected from being asymptomatic. As the disease progresses, symptoms may
...