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Essay / Research Paper Abstract
This 2 page paper provides an overview of questions related to the AIDS trials in Africa and Asia in the 1990s. When randomized clinical trials of plausible AIDS treatments were tested on HIV positive women in African and Asia in the 1990s, questions were raised about the ethics of these trials.
Page Count:
2 pages (~225 words per page)
File: MH11_MHAIDTRI.rtf
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Unformatted sample text from the term paper:
did seek out and secure consent from their subjects, written consent was not always possible or given, and this raised questions about the underlying method of seeking consent. In
essence, if women who are HIV positive and know they have a good chance of giving birth to an HIV infected infant without treatment and the cost of treatment is
either prohibitive or treatment is not available, the consent given to participate in a trial may be considered to be coerced. In understanding this statement, it is necessary to
relate some of the central elements of the Declaration of Helsinki. In defining t he ethical issues of these trials relative to the Declaration of Helsinki, it is necessary first
to recognize that these patients might have no access to treatment for their HIV infection during their pregnancy outside of the scope of the clinical trial. At the same
time, while the trial may promise the hope of improvements in their condition or the condition of their fetus, the use of a placebo for the control subjects in the
double-blind trials requires that some subjects will receive no treatment, though they may in fact believe they are receiving a treatment. This challenges one of the premises of the
Declaration of Helsinki, that it is the "duty of the physician to promote and safeguard the health of the people" (414). In fact, the physician is aware that some
of the people will be receiving possibly helpful treatments while others will not, and this appears to go against the assertion of the role of the physician. In the Declaration
of Helsinki, though, there is also a statement that physicians must recognize that a part of the research process requires the experimentation on human subjects and that risks may be
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